11/15/2011

SERTOLI-LEYDIG CELL TUMOR

During this past trip, a 21 year old female came to clinic with a pelvic mass. In 2010 she had a laparotomy with excision of her left ovary for a tumor. Unfortunately, she was lost to followup and never received chemotherapy. 

We reoperated on this patient. We found a tumor recurrence anterior to the bladder, which we resected. The pathology showed a Sertoli-Leydig cell tumor, which is a member of the sex cord-stromal tumors. This tumor can produce androgens (male hormones) in one third of patients and cause masculinization including acne and hirsutism, voice deepening, clitoromegally, temporal hair recession, and an increase in musculature. These tumors are sometimes called arrhenoblastomas or androblastomas.

Our patient recovered without difficulty and is now receiving chemotherapy.